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3WNG

Cyclic hexapeptide PKIDNp in complex with HIV-1 integrase

Summary for 3WNG
Entry DOI10.2210/pdb3wng/pdb
Related3WNE 3WNF 3WNH
Related PRD IDPRD_001214
DescriptorGag-Pol polyprotein, PKIDN(DPR) peptide, CADMIUM ION, ... (6 entities in total)
Functional Keywordsdna integration, aids, integrase, endonuclease, dna binding, viral protein, ledgf, lens epithelium-derived growth factor, rnaseh, poly nucleotidyl transferase, viral protein-peptide complex, viral protein/peptide
Biological sourceHuman immunodeficiency virus type 1 (HIV-1)
More
Cellular locationGag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P12497
Total number of polymer chains4
Total formula weight36667.26
Authors
Wielens, J.,Chalmers, D.K.,Parker, M.W. (deposition date: 2013-12-09, release date: 2013-12-25, Last modification date: 2024-10-30)
Primary citationNorthfield, S.E.,Wielens, J.,Headey, S.J.,Mulcair, M.,Scanlon, M.J.,Parker, M.W.,Thompson, P.E.,Chalmers, D.K.
Hexapeptide mimetics of LEDGF in complex with HIV-1 integrase
to be published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

226707

數據於2024-10-30公開中

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