3WNG
Cyclic hexapeptide PKIDNp in complex with HIV-1 integrase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Gag-Pol polyprotein | polymer | 157 | 17101.4 | 2 | UniProt (P12497) Pfam (PF00665) | Human immunodeficiency virus type 1 (HIV-1) | HIV-1 integrase |
| 2 | C, D (C, D) | PKIDN(DPR) peptide | polymer | 6 | 683.8 | 2 | BIRD (PRD_001214) | ||
| 3 | E, F, K, L (A, B) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
| 4 | G, M (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | H, I, J, N, O... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 6 | Q, R, S (A, B, D) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A, B: 56 - 212 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Ser 56 | Cys 1203 | engineered mutation |
| Gly 123 | Ser 1270 | engineered mutation |
| Ala 124 | Thr 1271 | engineered mutation |
| Arg 127 | Lys 1274 | engineered mutation |
| Asp 131 | Trp 1278 | engineered mutation |
| Asp 139 | Phe 1286 | engineered mutation |
| His 185 | Phe 1332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 35570.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1096.9 | |
| All* | Total formula weight | 36667.3 |
