3WNG
Cyclic hexapeptide PKIDNp in complex with HIV-1 integrase
Summary for 3WNG
Entry DOI | 10.2210/pdb3wng/pdb |
Related | 3WNE 3WNF 3WNH |
Related PRD ID | PRD_001214 |
Descriptor | Gag-Pol polyprotein, PKIDN(DPR) peptide, CADMIUM ION, ... (6 entities in total) |
Functional Keywords | dna integration, aids, integrase, endonuclease, dna binding, viral protein, ledgf, lens epithelium-derived growth factor, rnaseh, poly nucleotidyl transferase, viral protein-peptide complex, viral protein/peptide |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P12497 |
Total number of polymer chains | 4 |
Total formula weight | 36667.26 |
Authors | Wielens, J.,Chalmers, D.K.,Parker, M.W. (deposition date: 2013-12-09, release date: 2013-12-25, Last modification date: 2023-11-08) |
Primary citation | Northfield, S.E.,Wielens, J.,Headey, S.J.,Mulcair, M.,Scanlon, M.J.,Parker, M.W.,Thompson, P.E.,Chalmers, D.K. Hexapeptide mimetics of LEDGF in complex with HIV-1 integrase to be published, |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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