3WNE

Cyclic hexapeptide PKIDNG in complex with HIV-1 integrase

Summary for 3WNE

• Entry DOI: 10.2210/pdb3wne/pdb
• Related: 3WNF 3WNG 3WNH
• Related PRD ID: PRD_001211
• Descriptor: Gag-Pol polyprotein, LEDGF peptide, CADMIUM ION, ... (6 entities in total)
• Functional Keywords: dna integration, aids, integrase, endonuclease, polynucleotidyl transferase, dna binding, viral protein, rnaseh, ledgf, lens epithelium derived growth factor, viral protein-peptide complex, viral protein/peptide
• Biological source: Human immunodeficiency virus type 1 (HIV-1); More
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P12497
• Total number of polymer chains: 4
• Total formula weight: 36587.13

Authors

Wielens, J.,Chalmers, D.K.,Parker, M.W. (deposition date: 2013-12-09, release date: 2013-12-25, Last modification date: 2023-11-08)

• Primary citation: Northfield, S.E.,Wielens, J.,Headey, S.J.,Mulcair, M.,Scanlon, M.J.,Parker, M.W.,Thompson, P.E.,Chalmers, D.K.; Hexapeptide mimetics of LEDGF in complex with HIV-1 integrase; to be published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)