3W68
Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(4,5)-bisphosphate
Summary for 3W68
Entry DOI | 10.2210/pdb3w68/pdb |
Related | 3w67 |
Descriptor | Alpha-tocopherol transfer protein, (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, ... (6 entities in total) |
Functional Keywords | ataxia, vitamin e deficiency, aved, transfer protein, tocopherol, vitamin e, disease mutation, alpha-tocopherol transfer, alpha-tocopherol, phosphatidyl inositol phosphates, transport protein |
Biological source | Mus musculus (mouse) |
Cellular location | Cytoplasm (By similarity): Q8BWP5 |
Total number of polymer chains | 4 |
Total formula weight | 127383.27 |
Authors | |
Primary citation | Kono, N.,Ohto, U.,Hiramatsu, T.,Urabe, M.,Uchida, Y.,Satow, Y.,Arai, H. Impaired alpha-TTP-PIPs interaction underlies familial vitamin E deficiency Science, 340:1106-1110, 2013 Cited by PubMed: 23599266DOI: 10.1126/science.1233508 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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