3W68
Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(4,5)-bisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Alpha-tocopherol transfer protein | polymer | 266 | 30624.3 | 4 | UniProt (Q8BWP5) Pfam (PF03765) Pfam (PF00650) | Mus musculus (mouse) | Alpha-TTP |
| 2 | E, H, K, O (A, B, C, D) | (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL | non-polymer | 430.7 | 4 | Chemie (VIV) PubChem (2116) PubChem (21632387) PubChem (6033) PubChem (14985) PubChem (40970237) PubChem (1742129) PubChem (57470097) PubChem (1548900) PubChem (68099461) PubChem (9876542) PubChem (129628005) PubChem (6560141) PubChem (7059471) PubChem (121440693) PubChem (12359166) PubChem (12359167) PubChem (138470946) | |||
| 3 | F, G, J (A, B) | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE | non-polymer | 716.4 | 3 | Chemie (4PT) PubChem (21145415) PubChem (49866515) | |||
| 4 | I (B) | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE | non-polymer | 634.4 | 1 | Chemie (PBU) PubChem (60138181) PubChem (9543519) | |||
| 5 | L, M, N, P (C, D) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) PubChem (1061) | |||
| 6 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 278 (UniProt: Q8BWP5)
| PDB | External Database | Details |
|---|---|---|
| Gly 13 | - | expression tag |
| Pro 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Gly 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Glu 19 | - | expression tag |
| Phe 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 122497.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4886.1 | |
| All* | Total formula weight | 127383.3 |
