3W68
Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(4,5)-bisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Alpha-tocopherol transfer protein | polymer | 266 | 30624.3 | 4 | UniProt (Q8BWP5) Pfam (PF03765) Pfam (PF00650) | Mus musculus (mouse) | Alpha-TTP |
| 2 | E, H, K, O (A, B, C, D) | (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL | non-polymer | 430.7 | 4 | Chemie (VIV) | |||
| 3 | F, G, J (A, B) | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE | non-polymer | 716.4 | 3 | Chemie (4PT) | |||
| 4 | I (B) | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE | non-polymer | 634.4 | 1 | Chemie (PBU) | |||
| 5 | L, M, N, P (C, D) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 6 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 278 (UniProt: Q8BWP5)
| PDB | External Database | Details |
|---|---|---|
| Gly 13 | - | expression tag |
| Pro 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Gly 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Glu 19 | - | expression tag |
| Phe 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 122497.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4886.1 | |
| All* | Total formula weight | 127383.3 |
