3VTP
HIV fusion inhibitor MT-C34
Summary for 3VTP
Entry DOI | 10.2210/pdb3vtp/pdb |
Related | 3VGX 3VIE 3VTQ |
Descriptor | Transmembrane protein gp41 (3 entities in total) |
Functional Keywords | 6-helix-bundle, m-t hook, fusion inhibitor, membrane fusion, viral protein-antiviral protein complex, viral protein/antiviral protein |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P03377 P03377 |
Total number of polymer chains | 2 |
Total formula weight | 9407.60 |
Authors | Yao, X.,Waltersperger, S.,Wang, M.,Cui, S. (deposition date: 2012-06-02, release date: 2012-08-22, Last modification date: 2023-11-08) |
Primary citation | Chong, H.,Yao, X.,Sun, J.,Qiu, Z.,Zhang, M.,Waltersperger, S.,Wang, M.,Cui, S.,He, Y. The M-T hook structure is critical for design of HIV-1 fusion inhibitors. J.Biol.Chem., 287:34558-34568, 2012 Cited by PubMed: 22879603DOI: 10.1074/jbc.M112.390393 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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