3VOW

Crystal Structure of the Human APOBEC3C having HIV-1 Vif-binding Interface

Summary for 3VOW

Entry DOI	10.2210/pdb3vow/pdb
Descriptor	Probable DNA dC->dU-editing enzyme APOBEC-3C, ZINC ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	apobec3c, apobec3, antiviral deffense, host-virus interaction, metal-binding, hiv-1 vif, bet, single domain, sivagm, z2, hydrolase, hiv
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q9NRW3
Total number of polymer chains	2
Total formula weight	45869.98
Authors	Kitamura, S.,Suzuki, A.,Watanabe, N.,Iwatani, Y. (deposition date: 2012-02-22, release date: 2012-10-03, Last modification date: 2023-11-08)
Primary citation	Kitamura, S.,Ode, H.,Nakashima, M.,Imahashi, M.,Naganawa, Y.,Kurosawa, T.,Yokomaku, Y.,Yamane, T.,Watanabe, N.,Suzuki, A.,Sugiura, W.,Iwatani, Y. The APOBEC3C crystal structure and the interface for HIV-1 Vif binding. Nat.Struct.Mol.Biol., 19:1005-1010, 2012 Cited by PubMed: 23001005 DOI: 10.1038/nsmb.2378 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation