3VH7

Structure of HIV-1 gp41 NHR/fusion inhibitor complex P21

Summary for 3VH7

• Entry DOI: 10.2210/pdb3vh7/pdb
• Related: 3VGX 3VGY
• Descriptor: Envelope glycoprotein gp160, CP32M, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: 6-helix bundle, membrane fusion inhibition, membrane protein-inhibitor complex, membrane protein/inhibitor
• Biological source: Human immunodeficiency virus type 1 (HIV-1); More
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P03375
• Total number of polymer chains: 6
• Total formula weight: 32151.55

Authors

Yao, X.,Waltersperger, S.,Wang, M.T.,Cui, S. (deposition date: 2011-08-23, release date: 2012-06-13, Last modification date: 2023-11-08)

• Primary citation: Yao, X.,Chong, H.,Zhang, C.,Qiu, Z.,Qin, B.,Han, R.,Waltersperger, S.,Wang, M.T.,He, Y.,Cui, S.; Structural basis of potent and broad HIV-1 fusion inhibitor CP32M; J.Biol.Chem., 287:26618-26629, 2012; PubMed: 22679024; DOI: 10.1074/jbc.M112.381079

Experimental method

X-RAY DIFFRACTION (2.019 Å)