3VH7

Structure of HIV-1 gp41 NHR/fusion inhibitor complex P21

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Envelope glycoprotein gp160	polymer	58	6413.4	3	UniProt (P03375)	Human immunodeficiency virus type 1	Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 41, gp41
2	B, D, F (B, D, F)	CP32M	polymer	34	4295.7	3
3	G (E)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	H, I, J, K, L... (A, B, C, D, E...)	water	water		18.0	68	Chemie (HOH)

Sequence modifications

A, C, E: 546 - 588 (UniProt: P03375)

PDB	External Database	Details
Gly -10	-	expression tag
Ser -9	-	expression tag
Ala -8	-	expression tag
Met -7	-	expression tag
Ala -6	-	expression tag
Asp -5	-	expression tag
Ile -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Ser 1000	-	expression tag
Gly 1001	-	expression tag
Gly 1002	-	expression tag
Arg 1003	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	32127.2
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	32151.6

*Water molecules are not included.