3UZS
Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex
3UZS の概要
エントリーDOI | 10.2210/pdb3uzs/pdb |
関連するPDBエントリー | 1OMW 3UZT |
分子名称 | Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
機能のキーワード | protein-rna complex, protein kinase fold, rgs homology domain, pleckstrin homology domain, beta propeller, g protein-coupled receptor phosphorylation, rna aptamer, carboxymethylation, geranylgeranylation, transferase-rna complex, transferase/rna |
由来する生物種 | Bos taurus (bovine) 詳細 |
細胞内の位置 | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 134677.33 |
構造登録者 | |
主引用文献 | Tesmer, V.M.,Lennarz, S.,Mayer, G.,Tesmer, J.J. Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20:1300-1309, 2012 Cited by PubMed: 22727813DOI: 10.1016/j.str.2012.05.002 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (4.52 Å) |
構造検証レポート
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