3US2

Structure of p63 DNA Binding Domain in Complex with a 19 Base Pair A/T Rich Response Element Containing Two Half Sites with a Single Base Pair Overlap

Summary for 3US2

• Entry DOI: 10.2210/pdb3us2/pdb
• Related: 3QYM 3QYN 3US0 3US1
• Descriptor: Tumor protein 63, 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*AP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3', 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3', ... (4 entities in total)
• Functional Keywords: b-dna double helix, zinc binding, beta sandwich, greek key, transcription factor, nucleus, transcription activator-dna complex, transcription activator/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q9H3D4
• Total number of polymer chains: 12
• Total formula weight: 205283.42

Authors

Chen, C.,Herzberg, O. (deposition date: 2011-11-22, release date: 2012-02-01, Last modification date: 2024-02-28)

• Primary citation: Chen, C.,Gorlatova, N.,Herzberg, O.; Pliable DNA Conformation of Response Elements Bound to Transcription Factor p63.; J.Biol.Chem., 287:7477-7486, 2012; PubMed: 22247550; DOI: 10.1074/jbc.M111.315820

Experimental method

X-RAY DIFFRACTION (4.2 Å)