3UR9
1.65A resolution structure of Norwalk Virus Protease Containing a covalently bound dipeptidyl inhibitor
Summary for 3UR9
Entry DOI | 10.2210/pdb3ur9/pdb |
Related | 3UR6 4DCD 4F49 |
Descriptor | 3C-like protease, CHLORIDE ION, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, ... (4 entities in total) |
Functional Keywords | protease, norovirus, norwalk virus, antiviral inhibitors, dipeptidyl inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Norovirus |
Total number of polymer chains | 2 |
Total formula weight | 41365.18 |
Authors | Lovell, S.,Battaile, K.P.,Kim, Y.,Tiew, K.C.,Mandadapu, S.R.,Alliston, K.R.,Groutas, W.C.,Chang, K.O. (deposition date: 2011-11-21, release date: 2012-09-05, Last modification date: 2023-09-13) |
Primary citation | Kim, Y.,Lovell, S.,Tiew, K.C.,Mandadapu, S.R.,Alliston, K.R.,Battaile, K.P.,Groutas, W.C.,Chang, K.O. Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses. J.Virol., 86:11754-11762, 2012 Cited by PubMed: 22915796DOI: 10.1128/JVI.01348-12 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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