3UR9

1.65A resolution structure of Norwalk Virus Protease Containing a covalently bound dipeptidyl inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C-like protease	polymer	188	20126.1	2	UniProt (Q83883)	Norovirus	3CLpro
2	C, D, F, G (A, B)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
3	E, H (A, B)	(1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid	non-polymer		485.6	2	Chemie (K36)
4	I, J (A, B)	water	water		18.0	158	Chemie (HOH)

Sequence modifications

A, B: 1 - 181 (UniProt: Q83883)

PDB	External Database	Details
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40252.3
Non-Polymers*	Number of molecules	6
	Total formula weight	1112.9
All*	Total formula weight	41365.2

*Water molecules are not included.