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3UR6

1.5A resolution structure of apo Norwalk Virus Protease

Summary for 3UR6
Entry DOI10.2210/pdb3ur6/pdb
Related3P99 3UR9 4DCD 4F49
Descriptor3C-like protease (2 entities in total)
Functional Keywordsprotease, norovirus, norwalk virus, antiviral inhibitors, dipeptidyl inhibitor, hydrolase
Biological sourceNorovirus
Cellular locationProtein p48: Host membrane ; Single-pass membrane protein . NTPase: Host membrane ; Single- pass membrane protein . Protein p22: Host membrane ; Single-pass membrane protein : Q83883
Total number of polymer chains2
Total formula weight40252.26
Authors
Lovell, S.,Battaile, K.P.,Kim, Y.,Tiew, K.C.,Mandadapu, S.R.,Alliston, K.R.,Groutas, W.C.,Chang, K.O. (deposition date: 2011-11-21, release date: 2012-09-05, Last modification date: 2023-09-13)
Primary citationKim, Y.,Lovell, S.,Tiew, K.C.,Mandadapu, S.R.,Alliston, K.R.,Battaile, K.P.,Groutas, W.C.,Chang, K.O.
Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses.
J.Virol., 86:11754-11762, 2012
Cited by
PubMed: 22915796
DOI: 10.1128/JVI.01348-12
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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