Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3UMI

X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with zinc

Summary for 3UMI
Entry DOI10.2210/pdb3umi/pdb
Related3UMH 3UMK
DescriptorAmyloid beta A4 protein, ACETATE ION, ZINC ION, ... (5 entities in total)
Functional Keywordsmetal binding site, metal binding, cell surface, secretory pathway, metal binding protein
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein: P05067
Total number of polymer chains1
Total formula weight26086.14
Authors
Dahms, S.O.,Konnig, I.,Roeser, D.,Guhrs, K.H.,Than, M.E. (deposition date: 2011-11-13, release date: 2012-01-25, Last modification date: 2024-02-28)
Primary citationDahms, S.O.,Konnig, I.,Roeser, D.,Guhrs, K.H.,Mayer, M.C.,Kaden, D.,Multhaup, G.,Than, M.E.
Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
J.Mol.Biol., 416:438-452, 2012
Cited by
PubMed: 22245578
DOI: 10.1016/j.jmb.2011.12.057
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

数据于2024-03-27公开中

PDB statisticsPDBj update infoContact PDBjnumon