3UMI
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with zinc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Amyloid beta A4 protein | polymer | 211 | 25062.4 | 1 | UniProt (P05067) Pfam (PF12925) | Homo sapiens (human) | |
| 2 | B (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E, F, G, H... (A) | CADMIUM ION | non-polymer | 112.4 | 8 | Chemie (CD) | |||
| 5 | L (A) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A: 295 - 500 (UniProt: P05067)
| PDB | External Database | Details |
|---|---|---|
| Met 294 | - | initiating methionine |
| Ile 501 | - | expression tag |
| Glu 502 | - | expression tag |
| Gly 503 | - | expression tag |
| Arg 504 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25062.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1023.7 | |
| All* | Total formula weight | 26086.1 |
