3UG8
AKR1C3 complex with indomethacin at pH 7.5
Summary for 3UG8
Entry DOI | 10.2210/pdb3ug8/pdb |
Related | 1S2A 3UFY 3UGR |
Descriptor | Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, INDOMETHACIN, ... (5 entities in total) |
Functional Keywords | tim barrel, oxidoreductase, many small molecules, hormones, prostaglandins |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42330 |
Total number of polymer chains | 1 |
Total formula weight | 39140.63 |
Authors | Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.,Squire, C.J. (deposition date: 2011-11-02, release date: 2012-08-15, Last modification date: 2023-11-01) |
Primary citation | Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.Z.,Turnbull, A.P.,Squire, C.J. Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7:e43965-e43965, 2012 Cited by PubMed: 22937138DOI: 10.1371/journal.pone.0043965 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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