3UFY

AKR1C3 complex with R-naproxen

Summary for 3UFY

• Entry DOI: 10.2210/pdb3ufy/pdb
• Related: 3UG8 3UGR
• Descriptor: Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid, ... (5 entities in total)
• Functional Keywords: tim barrel, oxidoreductase, multiple small molecules
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P42330
• Total number of polymer chains: 1
• Total formula weight: 39261.37

Authors

Squire, C.J.,Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M. (deposition date: 2011-11-01, release date: 2012-08-15, Last modification date: 2023-11-01)

• Primary citation: Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.Z.,Turnbull, A.P.,Squire, C.J.; Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.; Plos One, 7:e43965-e43965, 2012; PubMed: 22937138; DOI: 10.1371/journal.pone.0043965

Experimental method

X-RAY DIFFRACTION (1.9 Å)