3TUH

Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib

Summary for 3TUH

• Entry DOI: 10.2210/pdb3tuh/pdb
• Descriptor: Heat shock protein HSP 90-alpha, 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one (3 entities in total)
• Functional Keywords: chaperone protein, atp binding, chaperone-inhibitor complex, chaperone/inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P07900
• Total number of polymer chains: 2
• Total formula weight: 47513.83

Authors

Ying, W. (deposition date: 2011-09-16, release date: 2012-09-19, Last modification date: 2024-02-28)

• Primary citation: Ying, W.; Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.8 Å)