3TUH

Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heat shock protein HSP 90-alpha	polymer	209	23392.5	2	UniProt (P07900) Pfam (PF13589)	Homo sapiens (human)	Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38
2	C, D (A, B)	5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one	non-polymer		364.4	2	Chemie (TUH)
3	E, F (A, B)	water	water		18.0	720	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46785.0
Non-Polymers*	Number of molecules	2
	Total formula weight	728.8
All*	Total formula weight	47513.8

*Water molecules are not included.