3TUH
Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Heat shock protein HSP 90-alpha | polymer | 209 | 23392.5 | 2 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (human) | Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38 |
| 2 | A, B | 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one | non-polymer | 364.4 | 2 | Chemie (TUH) | |||
| 3 | water | water | 18.0 | 720 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46785.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 728.8 | |
| All* | Total formula weight | 47513.8 |
