3TUH
Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 56.362, 88.878, 56.498 |
| Unit cell angles | 90.00, 99.41, 90.00 |
Refinement procedure
| Resolution | 47.220 - 1.800 |
| Rwork | 0.172 |
| R-free | 0.21250 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Refinement software | REFMAC (5.0) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 55.600 |
| High resolution limit [Å] | 1.740 |
| Number of reflections | 52765 |
| Completeness [%] | 93.6 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
