3TO7

Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated

Summary for 3TO7

• Entry DOI: 10.2210/pdb3to7/pdb
• Related: 3TO6 3TO9 3TOA 3TOB
• Descriptor: Histone acetyltransferase ESA1, COENZYME A, CACODYLIC ACID, ... (6 entities in total)
• Functional Keywords: myst family, histone acetyltransferase, transferase
• Biological source: Saccharomyces cerevisiae (Baker's yeast)
• Total number of polymer chains: 1
• Total formula weight: 34338.85

Authors

Yuan, H.,Ding, E.C.,Marmorstein, R. (deposition date: 2011-09-04, release date: 2011-11-09, Last modification date: 2023-12-06)

• Primary citation: Yuan, H.,Rossetto, D.,Mellert, H.,Dang, W.,Srinivasan, M.,Johnson, J.,Hodawadekar, S.,Ding, E.C.,Speicher, K.,Abshiru, N.,Perry, R.,Wu, J.,Yang, C.,Zheng, Y.G.,Speicher, D.W.,Thibault, P.,Verreault, A.,Johnson, F.B.,Berger, S.L.,Sternglanz, R.,McMahon, S.B.,Cote, J.,Marmorstein, R.; MYST protein acetyltransferase activity requires active site lysine autoacetylation.; Embo J., 31:58-70, 2011; PubMed: 22020126; DOI: 10.1038/emboj.2011.382

Experimental method

X-RAY DIFFRACTION (1.9 Å)