3TK6
factor Xa in complex with D46-5241
Summary for 3TK6
Entry DOI | 10.2210/pdb3tk6/pdb |
Related | 1V3X 1WU1 2D1J 2EI6 2EI7 2EI8 3TK5 |
Descriptor | Factor X heavy chain, Factor X light chain, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | glycoprotein, hydrolase, serine protease, plasma, blood, coagulation factor, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (HUMAN) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 2 |
Total formula weight | 32720.66 |
Authors | Suzuki, M.,Mochizuki, A.,Nagata, T.,Takano, H.,Kanno, H.,Kishida, M.,Ohta, T. (deposition date: 2011-08-25, release date: 2012-08-29, Last modification date: 2024-11-06) |
Primary citation | Mochizuki, A.,Nagata, T.,Takano, H.,Kanno, H.,Kishida, M.,Suzuki, M.,Ohta, T. Zwitter ionic potent durable orally active Factor Xa inhibitor. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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