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3TK6

factor Xa in complex with D46-5241

Functional Information from GO Data
ChainGOidnamespacecontents
A0004252molecular_functionserine-type endopeptidase activity
A0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A 261
ChainResidue
ATYR185
AASP185
AARG222
ALYS224
AHOH312
AHOH329

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A 262
ChainResidue
AGLU80
AHOH258
AHOH305
AASP70
AASN72
AGLN75

site_idAC3
Number of Residues20
DetailsBINDING SITE FOR RESIDUE D46 A 700
ChainResidue
AGLU97
ATHR98
ATYR99
AGLU147
APHE174
AASP189
AALA190
AVAL213
ATRP215
AGLY216
AGLU217
AGLY218
ACYS220
AGLY226
AILE227
ATYR228
AHOH310
AHOH342
AHOH350
AHOH355

Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC
ChainResidueDetails
ALEU53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPHV
ChainResidueDetails
AASP189-VAL200

site_idPS01186
Number of Residues16
DetailsEGF_2 EGF-like domain signature 2. CsCarGYtladngkaC
ChainResidueDetails
BCYS109-CYS124

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Charge relay system
ChainResidueDetails
AHIS57
AASP102
ASER195

227344

PDB entries from 2024-11-13

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