3TH2

Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+

Summary for 3TH2

• Entry DOI: 10.2210/pdb3th2/pdb
• Related: 2A2Q 3TH3 3TH4
• Descriptor: Coagulation factor VII light chain, CHLORIDE ION, Coagulation factor VII heavy chain, ... (11 entities in total)
• Functional Keywords: hydrolase, blood clotting, serine protease, blood coagulation, soluble tissue factor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 68637.72

Authors

Vadivel, K.,Agah, S.,Cascio, D.,Padmanabhan, K.,Bajaj, S.P. (deposition date: 2011-08-18, release date: 2012-08-22, Last modification date: 2023-12-06)

• Primary citation: Vadivel, K.,Agah, S.,Messer, A.,Cascio, D.,S Bajaj, M.,Krishnaswamy, S.,T Esmon, C.,Padmanabhan, K.,Bajaj, S.P.; Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+; To be Published,

Experimental method

X-RAY DIFFRACTION (1.72 Å)