3TH2
Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Coagulation factor VII light chain | polymer | 142 | 16359.8 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | Proconvertin, Serum prothrombin conversion accelerator, SPCA |
| 2 | B (H) | Coagulation factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | Proconvertin, Serum prothrombin conversion accelerator, SPCA |
| 3 | C (T) | Tissue factor | polymer | 205 | 23302.9 | 1 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) | Homo sapiens (human) | TF, Coagulation factor III, Thromboplastin |
| 4 | D (L) | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) | |||
| 5 | E (L) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 6 | F, I, L (L) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | G, H, J, K, M... (L, H) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 8 | N (H) | BENZAMIDINE | non-polymer | 120.2 | 1 | Chemie (BEN) | |||
| 9 | P (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 10 | Q, R (H, T) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 11 | S, T, U (L, H, T) | water | water | 18.0 | 586 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67766.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 871.7 | |
| All* | Total formula weight | 68637.7 |
