2A2Q
Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+
Summary for 2A2Q
Entry DOI | 10.2210/pdb2a2q/pdb |
Descriptor | Coagulation factor VII, CHLORIDE ION, P-AMINO BENZAMIDINE, ... (12 entities in total) |
Functional Keywords | factor viia, soluble tissue factor, mg2+, ca2+, na+, zn2+, hydrolase-blood clotting complex, hydrolase/blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 69947.32 |
Authors | Bajaj, S.P.,Bajaj, M.,Schmidt, A.E.,Padmanabhan, K. (deposition date: 2005-06-22, release date: 2006-07-04, Last modification date: 2023-11-15) |
Primary citation | Bajaj, S.P.,Schmidt, A.E.,Agah, S.,Bajaj, M.S.,Padmanabhan, K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J.Biol.Chem., 281:24873-24888, 2006 Cited by PubMed: 16757484DOI: 10.1074/jbc.M509971200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report