3T74

Thermolysin In Complex With UBTLN27

Summary for 3T74

• Entry DOI: 10.2210/pdb3t74/pdb
• Related: 3FLF 3FV4 3FVP 3FWD 3T73 3T87 3T8C 3T8D 3T8F 3T8G 3T8H
• Related PRD ID: PRD_000981
• Descriptor: Thermolysin, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-alanine, GLYCEROL, ... (7 entities in total)
• Functional Keywords: protease, metalloprotease, hydrolysis of peptide bonds, phosphoramidon, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bacillus thermoproteolyticus
• Cellular location: Secreted: P00800
• Total number of polymer chains: 1
• Total formula weight: 35696.37

Authors

Biela, A.,Heine, A.,Klebe, G. (deposition date: 2011-07-29, release date: 2012-08-01, Last modification date: 2023-09-13)

• Primary citation: Biela, A.,Betz, M.,Heine, A.,Klebe, G.; Water makes the difference: rearrangement of water solvation layer triggers non-additivity of functional group contributions in protein-ligand binding.; Chemmedchem, 7:1423-1434, 2012; PubMed: 22733601; DOI: 10.1002/cmdc.201200206

Experimental method

X-RAY DIFFRACTION (1.28 Å)