3T55

Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with Phenoxymethyl Benzoic Acid (PMBA)

3T55 の概要

• エントリーDOI: 10.2210/pdb3t55/pdb
• 関連するPDBエントリー: 3QJA 3T40 3T44 3T78
• 分子名称: Indole-3-glycerol phosphate synthase, 3-(phenoxymethyl)benzoic acid, MALONATE ION, ... (5 entities in total)
• 機能のキーワード: indole-3-glycerol phosphate synthase (igps), tryptophan biosynthesis, structural genomics, tb structural genomics consortium, tbsgc, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28479.44

構造登録者

Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2011-07-26, 公開日: 2012-08-08, 最終更新日: 2023-09-13)

• 主引用文献: Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.; Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis; To be Published,

実験手法

X-RAY DIFFRACTION (2.06 Å)