3T44

Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with indole glycerol phosphate (IGP) amd anthranilate

3T44 の概要

• エントリーDOI: 10.2210/pdb3t44/pdb
• 関連するPDBエントリー: 3QJA 3T40 3T55 3T78
• 分子名称: Indole-3-glycerol phosphate synthase, INDOLE-3-GLYCEROL PHOSPHATE, 2-AMINOBENZOIC ACID, ... (4 entities in total)
• 機能のキーワード: mycobacterium tuberculosis indole glycerol phosphate synthase (igps), tryptophan biosynthesis, structural genomics, tb structural genomics consortium, tbsgc, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28477.43

構造登録者

Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2011-07-25, 公開日: 2012-08-08, 最終更新日: 2023-11-15)

• 主引用文献: Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.; Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis; To be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)