3SXS

Crystal structure of BMX non-receptor tyrosine kinase complexed with PP2

Summary for 3SXS

• Entry DOI: 10.2210/pdb3sxs/pdb
• Related: 3SXR
• Descriptor: Cytoplasmic tyrosine-protein kinase BMX, 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE (3 entities in total)
• Functional Keywords: transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P51813
• Total number of polymer chains: 1
• Total formula weight: 31512.81

Authors

Sack, J.,Muckelbauer, J. (deposition date: 2011-07-15, release date: 2011-09-21, Last modification date: 2024-02-28)

• Primary citation: Muckelbauer, J.,Sack, J.S.,Ahmed, N.,Burke, J.,Chang, C.Y.,Gao, M.,Tino, J.,Xie, D.,Tebben, A.J.; X-ray crystal structure of bone marrow kinase in the x chromosome: a Tec family kinase.; Chem.Biol.Drug Des., 78:739-748, 2011; PubMed: 21883956; DOI: 10.1111/j.1747-0285.2011.01230.x

Experimental method

X-RAY DIFFRACTION (1.89 Å)