3SXS
Crystal structure of BMX non-receptor tyrosine kinase complexed with PP2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cytoplasmic tyrosine-protein kinase BMX | polymer | 268 | 31210.0 | 1 | UniProt (P51813) Pfam (PF07714) In PDB | Homo sapiens (human) | Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38 |
2 | A | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE | non-polymer | 302.8 | 1 | Chemie (PP2) | |||
3 | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A: 411 - 675 (UniProt: P51813)
PDB | External Database | Details |
---|---|---|
Gly 408 | - | expression tag |
His 409 | - | expression tag |
Met 410 | - | expression tag |
Lys 432 | Gln 432 | engineered mutation |
Met 611 | Gln 611 | engineered mutation |
Thr 617 | Asp 617 | engineered mutation |
Glu 620 | Gln 620 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31210.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 302.8 | |
All* | Total formula weight | 31512.8 |