3SXR
Crystal structure of BMX non-receptor tyrosine kinase complex with dasatinib
Summary for 3SXR
Entry DOI | 10.2210/pdb3sxr/pdb |
Related | 3SXS |
Descriptor | Cytoplasmic tyrosine-protein kinase BMX, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P51813 |
Total number of polymer chains | 2 |
Total formula weight | 63684.26 |
Authors | Sack, J.,Muckelbauer, J. (deposition date: 2011-07-15, release date: 2011-09-21, Last modification date: 2024-02-28) |
Primary citation | Muckelbauer, J.,Sack, J.S.,Ahmed, N.,Burke, J.,Chang, C.Y.,Gao, M.,Tino, J.,Xie, D.,Tebben, A.J. X-ray crystal structure of bone marrow kinase in the x chromosome: a Tec family kinase. Chem.Biol.Drug Des., 78:739-748, 2011 Cited by PubMed: 21883956DOI: 10.1111/j.1747-0285.2011.01230.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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