Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 1N1 A 1 |
| Chain | Residue |
| A | LEU423 |
| A | SER493 |
| A | GLY495 |
| A | SER553 |
| A | PHE555 |
| B | LEU420 |
| A | VAL431 |
| A | ALA443 |
| A | LYS445 |
| A | ILE487 |
| A | THR489 |
| A | GLU490 |
| A | TYR491 |
| A | ILE492 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 676 |
| Chain | Residue |
| A | HOH81 |
| A | HOH115 |
| A | HOH148 |
| A | TYR586 |
| A | SER607 |
| A | LYS610 |
| A | TYR632 |
| A | PRO634 |
| A | HIS635 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 1N1 B 2 |
| Chain | Residue |
| B | HOH116 |
| B | HOH157 |
| B | LEU423 |
| B | VAL431 |
| B | ALA443 |
| B | LYS445 |
| B | ILE487 |
| B | THR489 |
| B | GLU490 |
| B | TYR491 |
| B | ILE492 |
| B | SER493 |
| B | GLY495 |
| B | SER553 |
| B | PHE555 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 676 |
| Chain | Residue |
| A | VAL567 |
| A | SER568 |
| B | HOH227 |
| B | GLY408 |
| B | HIS409 |
| B | MET410 |
| B | GLU411 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 3 |
| Chain | Residue |
| B | LYS610 |
| B | TYR632 |
| B | PRO634 |
| B | HIS635 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 23 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGSGQFGVVKlGkwkgqyd...........VAVK |
| Chain | Residue | Details |
| A | LEU423-LYS445 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FIHrDLAARNCLV |
| Chain | Residue | Details |
| A | PHE532-VAL544 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Motif: {"description":"CAV1-binding"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by SRC and autocatalysis","evidences":[{"source":"PubMed","id":"10688651","evidenceCode":"ECO:0000269"}]} |
