3SL9
X-ray structure of Beta catenin in complex with Bcl9
Summary for 3SL9
Entry DOI | 10.2210/pdb3sl9/pdb |
Related | 2GL7 3SLA |
Descriptor | Catenin beta-1, B-cell CLL/lymphoma 9 protein, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | armadillo repeat, components of the wnt signaling pathway, beta catenin, signaling protein, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P35222 Nucleus (By similarity): O00512 |
Total number of polymer chains | 8 |
Total formula weight | 99549.13 |
Authors | |
Primary citation | de la Roche, M.,Rutherford, T.J.,Gupta, D.,Veprintsev, D.B.,Saxty, B.,Freund, S.M.,Bienz, M. An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nat Commun, 3:680-680, 2012 Cited by PubMed: 22353711DOI: 10.1038/ncomms1680 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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