3SI8
Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2)
Replaces: 3MR4Summary for 3SI8
Entry DOI | 10.2210/pdb3si8/pdb |
Related | 3MR2 3MR3 3MR5 3MR6 |
Descriptor | DNA polymerase eta, COBALT (II) ION, DNA (5'-D(*TP*A*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*C)-3'), ... (11 entities in total) |
Functional Keywords | protein-dna complex, multiple domains, three are alpha/beta fold and one of the four is helical fold, dna polymerase, dna binding, mg2+ and dntp binding, affinity tag is added and partially removed at the n-terminal end, nucleus, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9Y253 |
Total number of polymer chains | 3 |
Total formula weight | 57503.69 |
Authors | Biertumpfel, C.,Zhao, Y.,Kondo, Y.,Ramon-Maiques, S.,Gregory, M.,Lee, J.Y.,Masutani, C.,Lehmann, A.R.,Hanaoka, F.,Yang, W. (deposition date: 2011-06-17, release date: 2011-08-03, Last modification date: 2024-03-13) |
Primary citation | Biertumpfel, C.,Zhao, Y.,Kondo, Y.,Ramon-Maiques, S.,Gregory, M.,Lee, J.Y.,Masutani, C.,Lehmann, A.R.,Hanaoka, F.,Yang, W. Structure and mechanism of human DNA polymerase eta. Nature, 465:1044-1048, 2010 Cited by PubMed: 20577208DOI: 10.1038/nature09196 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report