3SI5

Kinetochore-BUBR1 kinase complex

Summary for 3SI5

Entry DOI	10.2210/pdb3si5/pdb
Related	2I3S 2LAH 2WVI 3E7E 3ESL
Descriptor	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein CASC5 (3 entities in total)
Functional Keywords	bubr1-blinkin complex, mitotic checkpoint, bubr1, blinkin/knl1, chromosome segregation, cell cycle
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: O60566 Nucleus: Q8NG31
Total number of polymer chains	4
Total formula weight	46471.26
Authors	Blundell, T.L.,Chirgadze, D.Y.,Bolanos-Garcia, V.M. (deposition date: 2011-06-17, release date: 2011-10-26, Last modification date: 2023-09-13)
Primary citation	Bolanos-Garcia, V.M.,Lischetti, T.,Matak-Vinkovic, D.,Cota, E.,Simpson, P.J.,Chirgadze, D.Y.,Spring, D.R.,Robinson, C.V.,Nilsson, J.,Blundell, T.L. Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site. Structure, 19:1691-1700, 2011 Cited by PubMed: 22000412 DOI: 10.1016/j.str.2011.09.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation