3SFM
Novel crystallization conditions for tandem variant R67 DHFR yields wild-type crystal structure
Summary for 3SFM
Entry DOI | 10.2210/pdb3sfm/pdb |
Descriptor | Dihydrofolate reductase type 2, (4R)-2-METHYLPENTANE-2,4-DIOL (3 entities in total) |
Functional Keywords | oxidoreductase, dihydrofolate reductase, antibiotic resistance, in situ proteolysis, type ii dhfr, sh3, reductase, dhf and nadph-binding |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 7088.03 |
Authors | Yachnin, B.J.,Berghuis, A.M. (deposition date: 2011-06-13, release date: 2011-11-02, Last modification date: 2023-09-13) |
Primary citation | Yachnin, B.J.,Colin, D.Y.,Volpato, J.P.,Ebert, M.,Pelletier, J.N.,Berghuis, A.M. Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure. Acta Crystallogr.,Sect.F, 67:1316-1322, 2011 Cited by PubMed: 22102224DOI: 10.1107/S1744309111030417 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
Download full validation report