3SFM
Novel crystallization conditions for tandem variant R67 DHFR yields wild-type crystal structure
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydrofolate reductase type 2 | polymer | 62 | 6733.5 | 1 | UniProt (P00383) Pfam (PF06442) In PDB | Escherichia coli | Dihydrofolate reductase type II |
2 | A | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 3 | Chemie (MRD) | |||
3 | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A: 21 - 78 (UniProt: P00383)
PDB | External Database | Details |
---|---|---|
Asp 21 | Asn 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 6733.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 354.5 | |
All* | Total formula weight | 7088.0 |