3RME
AMCase in complex with Compound 5
Summary for 3RME
Entry DOI | 10.2210/pdb3rme/pdb |
Related | 3RM4 3RM8 3RM9 |
Descriptor | Acidic mammalian chitinase, GLYCEROL, N-ethyl-2-(4-methylpiperazin-1-yl)pyridine-3-carboxamide, ... (4 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: Q9BZP6 |
Total number of polymer chains | 2 |
Total formula weight | 89087.58 |
Authors | |
Primary citation | Cole, D.C.,Olland, A.M.,Jacob, J.,Brooks, J.,Bursavich, M.G.,Czerwinski, R.,Declercq, C.,Johnson, M.,Joseph-McCarthy, D.,Ellingboe, J.W.,Lin, L.,Nowak, P.,Presman, E.,Strand, J.,Tam, A.,Williams, C.M.M.,Yao, S.,Tsao, D.H.H.,Fitz, L.J. Identification and Characterization of Acidic Mammalian Chitinase Inhibitors J.Med.Chem., 53:6122-6128, 2010 Cited by PubMed: 20666458PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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