3RME

AMCase in complex with Compound 5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acidic mammalian chitinase	polymer	395	44203.4	2	UniProt (Q9BZP6) Pfam (PF00704) In PDB	Homo sapiens (human)	AMCase, Lung-specific protein TSA1902
2	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	A, B	N-ethyl-2-(4-methylpiperazin-1-yl)pyridine-3-carboxamide	non-polymer		248.3	2	Chemie (RME)
4		water	water		18.0	589	Chemie (HOH)

Sequence modifications

A, B: 22 - 408 (UniProt: Q9BZP6)

PDB	External Database	Details
Asp 45	Asn 45	variant
Asn 47	Asp 47	variant
Met 61	Arg 61	variant
Val 339	Ile 339	variant
Gly 409	-	EXPRESSION TAG
Ser 410	-	EXPRESSION TAG
His 411	-	EXPRESSION TAG
His 412	-	EXPRESSION TAG
His 413	-	EXPRESSION TAG
His 414	-	EXPRESSION TAG
His 415	-	EXPRESSION TAG
His 416	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88406.7
Non-Polymers*	Number of molecules	4
	Total formula weight	680.8
All*	Total formula weight	89087.6

*Water molecules are not included.