3RHJ

Crystal structure of the E673A mutant of the C-terminal domain of RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with co-purified NADP

Summary for 3RHJ

Entry DOI	10.2210/pdb3rhj/pdb
Related	3RHL 3RHM 3RHO 3RHP 3RHQ 3RHR
Descriptor	Aldehyde dehydrogenase 1 family, member L1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	fdh, oxidoreductase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Total number of polymer chains	4
Total formula weight	231901.54
Authors	Tsybovsky, Y. (deposition date: 2011-04-11, release date: 2011-04-27, Last modification date: 2023-09-13)
Primary citation	Tsybovsky, Y.,Krupenko, S.A. Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme. J.Biol.Chem., 286:23357-23367, 2011 Cited by PubMed: 21540484 DOI: 10.1074/jbc.M111.221069 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation