3QX8

Crystal structure of MID domain from hAGO2 in complex with m7GpppG

Summary for 3QX8

• Entry DOI: 10.2210/pdb3qx8/pdb
• Related: 3LUC
• Descriptor: Protein argonaute-2, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE (3 entities in total)
• Functional Keywords: rossmann-like folde, rna binding, small rna, rna binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, P-body: Q9UKV8
• Total number of polymer chains: 3
• Total formula weight: 48388.18

Authors

Frank, F.,Fabian, M.R.,Stepinski, J.,Jemielity, J.,Darzynkiewicz, E.,Sonenberg, N.,Nagar, B. (deposition date: 2011-03-01, release date: 2011-04-20, Last modification date: 2023-09-13)

• Primary citation: Frank, F.,Fabian, M.R.,Stepinski, J.,Jemielity, J.,Darzynkiewicz, E.,Sonenberg, N.,Nagar, B.; Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain.; Embo Rep., 12:415-420, 2011; PubMed: 21475248; DOI: 10.1038/embor.2011.48

Experimental method

X-RAY DIFFRACTION (2.3 Å)