3QX8
Crystal structure of MID domain from hAGO2 in complex with m7GpppG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Protein argonaute-2 | polymer | 138 | 15326.0 | 3 | UniProt (Q9UKV8) Pfam (PF16487) | Homo sapiens (human) | Argonaute2, hAgo2, Eukaryotic translation initiation factor 2C 2, eIF-2C 2, eIF2C 2, PAZ Piwi domain protein, PPD, Protein slicer |
| 2 | D, E, F (A, B, C) | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE | non-polymer | 803.4 | 3 | Chemie (GTG) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B, C: 439 - 575 (UniProt: Q9UKV8)
| PDB | External Database | Details |
|---|---|---|
| Ser 438 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45977.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 2410.3 | |
| All* | Total formula weight | 48388.2 |
