3QFJ

The complex between TCR A6 and human Class I MHC HLA-A2 with the modified TAX (Y5F) peptide

Summary for 3QFJ

Entry DOI	10.2210/pdb3qfj/pdb
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, TAX(Y5F) peptide, ... (7 entities in total)
Functional Keywords	tax peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, y5f mutation, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769
Total number of polymer chains	5
Total formula weight	95250.40
Authors	Borbulevych, O.Y.,Baker, B.M. (deposition date: 2011-01-21, release date: 2012-01-11, Last modification date: 2023-09-13)
Primary citation	Scott, D.R.,Borbulevych, O.Y.,Piepenbrink, K.H.,Corcelli, S.A.,Baker, B.M. Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism. J.Mol.Biol., 414:385-400, 2011 Cited by PubMed: 22019736 DOI: 10.1016/j.jmb.2011.10.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation