3QB4
Crystal structure of a TGF-beta ligand-receptor complex
Summary for 3QB4
Entry DOI | 10.2210/pdb3qb4/pdb |
Related | 1REW 1WAQ 2K3G 3EVS 3NH7 |
Descriptor | Growth/differentiation factor 5, Bone morphogenetic protein receptor type-1A (3 entities in total) |
Functional Keywords | cystine-knot, ligand-receptor complex, protein, membrane/extracellular, cytokine-transferase receptor complex, cytokine/transferase receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted : P43026 Membrane; Single-pass type I membrane protein: P36894 |
Total number of polymer chains | 4 |
Total formula weight | 55987.63 |
Authors | Mueller, T.D.,Nickel, J.,Sebald, W. (deposition date: 2011-01-12, release date: 2012-03-14, Last modification date: 2023-09-13) |
Primary citation | Klammert, U.,Mueller, T.D.,Hellmann, T.V.,Wuerzler, K.K.,Kotzsch, A.,Schliermann, A.,Schmitz, W.,Kuebler, A.C.,Sebald, W.,Nickel, J. GDF-5 can act as a context-dependent BMP-2 antagonist. Bmc Biol., 13:77-77, 2015 Cited by PubMed: 26385096DOI: 10.1186/s12915-015-0183-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
Download full validation report