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3PWK

Crystal Structure of Aspartate beta-Semialdehide Dehydrogenase from Streptococcus pneumoniae with 2',5'-Adenosine diphosphate and D-2-aminoadipate

Summary for 3PWK
Entry DOI10.2210/pdb3pwk/pdb
Related2GZ2 3PWS 3PYL 3PYX 3PZB 3PZR 3Q0E 3Q11 3Q1L
DescriptorAspartate-semialdehyde dehydrogenase, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE, trans-cyclohexane-1,4-dicarboxylic acid, ... (6 entities in total)
Functional Keywordsdehydrogenase, nadp binding, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceStreptococcus pneumoniae
Total number of polymer chains2
Total formula weight82975.19
Authors
Pavlovsky, A.G.,Viola, R.E. (deposition date: 2010-12-08, release date: 2012-01-04, Last modification date: 2023-09-13)
Primary citationPavlovsky, A.G.,Liu, X.,Faehnle, C.R.,Potente, N.,Viola, R.E.
Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79:128-136, 2012
Cited by
PubMed: 22039970
DOI: 10.1111/j.1747-0285.2011.01267.x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

217705

건을2024-03-27부터공개중

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