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3PUI

Cocaine Esterase with mutations G4C, S10C

Summary for 3PUI
Entry DOI10.2210/pdb3pui/pdb
Related1ju3 1ju4 3PUH 3i2f 3i2g 3i2h 3i2i 3i2j 3ida
DescriptorCocaine esterase, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
Functional Keywordsalpha/beta hydrolase, jelly-roll beta-barrel, cleavage of cocaine, hydrolase
Biological sourceRhodococcus sp.
Cellular locationCytoplasm : Q9L9D7
Total number of polymer chains1
Total formula weight63972.50
Authors
Nance, M.R.,Tesmer, J.J.G. (deposition date: 2010-12-04, release date: 2011-09-21, Last modification date: 2023-09-06)
Primary citationNarasimhan, D.,Collins, G.T.,Nance, M.R.,Nichols, J.,Edwald, E.,Chan, J.,Ko, M.C.,Woods, J.H.,Tesmer, J.J.,Sunahara, R.K.
Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
Mol.Pharmacol., 80:1056-1065, 2011
Cited by
PubMed: 21890748
DOI: 10.1124/mol.111.074997
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.53 Å)
Structure validation

217705

數據於2024-03-27公開中

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