3PUI
Cocaine Esterase with mutations G4C, S10C
Summary for 3PUI
Entry DOI | 10.2210/pdb3pui/pdb |
Related | 1ju3 1ju4 3i2f 3i2g 3i2h 3i2i 3i2j 3ida 3PUH |
Descriptor | Cocaine esterase, CHLORIDE ION, SODIUM ION, ... (4 entities in total) |
Functional Keywords | alpha/beta hydrolase, jelly-roll beta-barrel, cleavage of cocaine, hydrolase |
Biological source | Rhodococcus sp. |
Cellular location | Cytoplasm : Q9L9D7 |
Total number of polymer chains | 1 |
Total formula weight | 63972.50 |
Authors | Nance, M.R.,Tesmer, J.J.G. (deposition date: 2010-12-04, release date: 2011-09-21, Last modification date: 2023-09-06) |
Primary citation | Narasimhan, D.,Collins, G.T.,Nance, M.R.,Nichols, J.,Edwald, E.,Chan, J.,Ko, M.C.,Woods, J.H.,Tesmer, J.J.,Sunahara, R.K. Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time. Mol.Pharmacol., 80:1056-1065, 2011 Cited by PubMed: 21890748DOI: 10.1124/mol.111.074997 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
Download full validation report